Cawsam BioProcess Consulting is an independent consultancy led by Martin Smith, providing expert bioprocess support from bench to 20,000L commercial scale. GMP manufacturing, tech transfer, process development and facility design across monoclonal antibodies, viral vectors, recombinant proteins, cell therapy and cultivated meat.
Including tech transfer lead on AZD1222 — Oxford-AstraZeneca COVID-19 vaccine
End-to-end bioprocess support across the full development and manufacturing lifecycle
Upstream and downstream process development for mAbs, recombinant proteins, viral vectors (AAV, lentiviral), vaccines and cell therapies. Bench to pilot scale optimisation using DoE methodologies.
GMP tech transfer from development to manufacturing scale. Proven track record from bench to 20,000L bioreactor scale. Regulatory package preparation for IND/BLA submissions.
Design and specification of GMP bioprocessing facilities from concept to operational handover. Equipment selection, cleanroom design, environmental monitoring systems, buffer and media preparation at scale.
Request for proposal preparation, CMO/CDMO evaluation and selection. Ongoing technical oversight of outsourced manufacturing programmes.
GMP operations, quality systems and regulatory strategy. Experience supporting EMA Emergency Use Authorisation and IND/BLA submissions across multiple modalities.
Lean Six Sigma Black Belt. Process optimisation, capacity modelling, cost of goods analysis. Delivered 41% business growth at Lonza and 50% DSP capacity increase without process changes.
Broad experience across biological modalities
A track record built across the industry's leading organisations
With over 25 years of experience spanning process development, GMP manufacturing, technology transfer and facility design, Martin Smith brings rare end-to-end expertise to every engagement.
Martin's career has taken him from early-stage academic translation through to large-scale commercial manufacturing at some of the world's leading biopharmaceutical organisations — including Lonza, Merck and AstraZeneca.
As Tech Transfer Lead for the Oxford-AstraZeneca COVID-19 vaccine (AZD1222), Martin supported the batch production and regulatory package that led to the EMA Emergency Use Authorisation — one of the most consequential bioprocess programmes of the last decade.
Cawsam BioProcess Consulting was founded in 2022 to bring this depth of experience directly to clients who need it most — whether that's a startup navigating their first GMP campaign, a pharma company evaluating CMO partners, or a research group translating a promising therapy toward clinical use.
Cawsam Bio provides expert consultancy in bioprocess development, GMP manufacturing, technology transfer and scale-up, facility design and start-up, CMO/CDMO selection and management, and regulatory and GMP compliance. We work across monoclonal antibodies, viral vectors, vaccines, cell therapy and cultivated meat.
Martin Smith is the founder and lead consultant at Cawsam BioProcess Consulting. He holds a PhD in Biochemical Engineering from University College London (UCL) and has over 25 years of industry experience at Lonza, Merck and AstraZeneca. Martin served as Tech Transfer Lead for the Oxford-AstraZeneca COVID-19 vaccine (AZD1222), supporting the EMA Emergency Use Authorisation.
Cawsam Bio has experience across monoclonal antibodies (mAbs), viral vectors (AAV, lentiviral), recombinant proteins, vaccines (VLP, plasmid DNA), cell therapy, cultivated meat, antibody drug conjugates and gene therapy.
Contact Martin Smith directly at martin@cawsambio.com or use the contact form below to describe your project. Cawsam Bio works with startups, pharma companies, research groups and CDMOs worldwide.
Cawsam Bio supports projects from bench scale through to 20,000L commercial bioreactor scale, covering the full lifecycle from early process development through GMP manufacturing and regulatory submission.
Whether you're at the earliest stages of process development or need experienced oversight of a complex manufacturing programme — get in touch to discuss how Cawsam Bio can help.